6-Isobutylquinoline is achromatic crystal, melting point 26.48 ℃, 242.2℃boiling point ( 99.1kPa ), the about body of 1.09101 ( 30/4 ℃), refractive basis 1.62078 ( 30 ℃), beam is 107 ℃. With a array of amoebic solvents miscible, acrid in adulterate acid; with water, acrid than quinoline; agnate to anise oil and methyl phenyl ether smell. With the beef can be volatile. Afterwards storage, the blush yellow. PKa=5.4, acrid hardly stronger than quinoline, can become a alkali and acid: its hydrochloride, melting point 209 ℃, melting point 223 ℃picrate. N can action acylation and alkylation reaction, its melting point is 159 ℃methiodide. Electrophilic barter occurs in the 5 or 8 bits. Nucleophilic barter occurs in 1. Susceptible to blaze and abridgement reaction. Found in atramentous tar, authoritative accessible than Zeller – Na Pierre Lars Ki amalgam or Pomerantz – Selfridge reaction. Containing isoquinoline ring some important alkaloids. Can accomplish drugs and insecticide, blaze can be fabricated afterwards pyridine carboxylic acid, its acquired can be acclimated in the accomplish of blush blur and dye. Acclimated as average and constructed drugs, dyes, pesticides, gas chromatography anchored liquid. Industry mainly atramentous tar awkward quinoline atom as raw material, through sulfonation, apportioned crystallization, filtration, crystallization, ammonia decomposition, abrasion and beverage of isoquinoline.

6-Isobutylquinoline agnate actinic backdrop and pyridine and quinoline, protonation, alkylation, acylation and peracetic acerbic blaze is agitated out in the N atom, electrophilic ambrosial barter and nucleophilic ambrosial barter acknowledgment mainly in the ring of the C atoms on the. Isoquinoline electrophilic ambrosial barter action than pyridine, preferentially occurred in the isoquinoline ring 5- and 8-, mainly in 5- products. For C- protonated benzene ring and proton barter through the N- protonated acerbic sulfate, charge this, but the acknowledgment in C-5 than C-8. Nucleophilic ambrosial barter in heterocyclic isoquinoline, preferentially occurred at 1-. For example, isoquinoline afterwards Chichibabin acknowledgment is 1- aminoisoquinolines; with n-butyl lithium Ziegler acknowledgment is 1- butyl isoquinoline, this acknowledgment an accession artefact of 1- butyl -1,2- two hydrogen isoquinoline afflicted alloyed benzene rings are stabilized, can be separated, by nitrobenzene blaze alter the carbon, aromaticity and restore the isoquinoline ring. Isoquinoline beneath top temperature into the breeze of hydrogen and hydroxide acknowledgment and absolute hydroxylation, the artefact is 1- isoquinolone.

more about: 6-Isobutylquinoline Price

from: Fluorides Chemical