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Monthly Archives: July 2013

Product name: Anti-CD272/BTLA (B and T lymphocyte attenuator)
Description: CD272 is a lymphocyte inhibitory receptor. It is a third affiliate of co-inhibitory receptors of the CD28 immunoglobulin superfamily with similarities to (CTLA) -4 and (PD) -1 and interacts with a B7 homolog, B7H4. CD272 is constitutively bidding on a lot of CD4 + and CD8 + T beef and its announcement progressively decreases aloft T corpuscle activation. It charcoal bidding on Th1 beef but not Th2 cells. CD272 is a different co-receptor which interacts with the bump afterlife agency receptor superfamily affiliate herpesvirus access advocate (HVEM) and this alternation is an important alleyway acclimation lymphocyte activation and / or homeostasis in the allowed acknowledgment and ability aswell play an important role in the aliment of T corpuscle tolerance.

 

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