Black pepper as a traditional herbal medicine for the treatment of many diseases, is one of important medicinal materials. As early as the end of the 19th century, as the main ingredient of pepper, pepper alkali have been purified and synthesis, but less research on the pharmacological effects. With the development of the technology of modern pharmacology, pharmacology of piperine have further understanding, summarized as follows: 1, the influence of piperine on the central nervous system, the chemical structure of piperine belongs to cinnamon amides, Cui Guangzhi in China and other research prove that piperine has sedative and hypnotic, anticonvulsants, skeletal muscle relaxation and the pharmacological action of antidepressant, etc. By intraperitoneal injection of sedative hypnotic effects of the piperine: piperine 10, 20, 40 mg kg. Colorless monoclinic prismatic crystals.

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