Padimate O is an amoebic admixture accompanying to the water-soluble admixture PABA (4-aminobenzoic acid) that is acclimated as an additive in some sunscreens. This bare water-insoluble adipose aqueous is an ester formed by the abstract of 2-ethylhexanol with dimethylaminobenzoic acid. Other names for padimate O cover 2-ethylhexyl 4-dimethylaminobenzoate, Escalol 507, octyldimethyl PABA, and OD-PABA.
Padimate O absorbs ultraviolet rays, thereby preventing absolute DNA accident by UV-B. However, the thus-excited padimate O kernel may again acknowledge with DNA to aftermath aberrant DNA damage, agnate to the furnishings of ionizing radiation. An in vitro aggrandize abstraction conducted in 1993 approved the sunlight-induced mutagenicity of padimate O. The photobiological backdrop of padimate O resemble those of Michler’s ketone, which is advised photocarcinogenic in rats and mice. These allegation advance that padimate O ability aswell be photocarcinogenic.
However, assorted in vivo studies conducted in baldheaded mice afterward contemporary appliance of padimate O accept approved no baleful furnishings and that padimate O reduces the amount of and delays the actualization of UV-induced derma tumors.