Ketanserin (CAS 74050-98-9) Description

Synonym: 3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2,4(1H,3H)-quinazolinedione

CAS Number:   74050-98-9

Purity:      ≥99%

Molecular Weight:   395.43

Molecular Formula: C22H22FN3O3

Appearance:    Crystalline powder

Solubility: Soluble in water (<1 mg/ml at 25 °C), DMSO (2 mg/ml at 25 °C), ethanol (<1 mg/ml at 25 °C), DMF (10 mg/ml), and methanol.

Melting Point: 228-232 °C

Boiling Point:   607.53 °C (Predicted)

Density:   1.28 g/cm3 at 20 °C

Application:      A selective serotonin antagonist

Storage:   Store at room temperature

Description:

Ketanserin is a selective serotonin receptor antagonist with weak adrenergic receptor blocking properties. The drug is effective in lowering blood pressure in essential hypertension. It also inhibits platelet aggregation. It is well tolerated and is particularly effective in older patients.

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