Doxycycline is a anesthetic which will accommodate you with able aegis adjoin malaria if taken correctly.

Expired tetracyclines or tetracyclines accustomed to angle at a pH beneath than 2 are appear to be nephrotoxic due to the accumulation of a abasement product, anhydro-4-epitetracycline causing Fanconi syndrome. In the case of doxycycline, the absence of a hydroxyl accumulation in C-6 prevents the accumulation of the nephrotoxic compound. Nevertheless, tetracyclines and doxycycline itself accept to be taken with anticipation in patients with branch injury, as they can aggravate azotemia due to catabolic effects.